hClaudin 6(CLDN6)/CHO
CBP74181
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I. Background | |
CLDNs 是上皮细胞紧密连接的主要成分。CLDN6 是紧密连接家族(CLDNs)的一员,是一个四次跨膜蛋白,具有较短的胞质 N 端和 C 端胞质结构域、两个胞外结构域(较大的 ECL1 和较小的 ECL2)和一个短的胞内环。CLDN6 可参与乳腺癌、胃癌、肝细胞癌等多种恶性肿瘤的发生发展。CLDN6 具有重要的生物学功能,其异常表达与丙型肝炎感染有关。 | |
II. Introduction | |
Host Cell: | CHO |
Expressed gene: | Claudin 6(CLDN6) |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5ug/ml puromycin |
Storage: | Liquid nitrogen |
Application(s): | Binding Assay,FACS |
III. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Disease: | Hamster Chinese ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
IV. Representative Data | |
Figure 1.Recombinant CLDN6/CHO constitutively expressing CLDN6. |
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