TOV-112D（人卵巢癌细胞）
CBP60694
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| I. General information | |
| Synonyms: | TOV-112D |
| Background: | This cell line was initiated in October of 1992 from a patient with early onset ovarian cancer. The patient was of French-Canadian descent with an unknown family history of ovarian cancer. |
| Species: | Homo sapiens, human |
| Tissue: | Ovary |
| Disease: | grade 3, stage IIIC, primary malignant adenocarcinoma; endometrioid carcinoma |
| Gender: | Caucasian, female, 42years adult |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X CSF1PO: 12 D13S317: 8 D16S539: 9,12 D5S818: 10 D7S820: 9,10 THO1: 6 TPOX: 8,11 vWA: 18 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
1:1 mixture of MCDB 105 medium and Medium 199,85%; FBS,15% TOV-112D完全培养基，# CBP60694M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Oncogene: | her2/neu +, p53 (mutated, Arg --> His mutation at exon 6, codon 175) Ref |
| Genes Expressed: | keratin |
| Cellular Products: | keratin |
| Tumor Formation: | The cells are tumorigenic in nude mice and form colonies in soft agar |
| Comments: | Unlike TOV-21G (ATCC CRL-11730) and OV-90 (ATCC CRL-11732), the TOV-112D cell line does not exhibit a deletion at chromosome 3p24. For more information, please contact Cobioer (4008-750-250). |
