SNU-1（人胃癌细胞）
CBP60501
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| I. General information | |
| Synonyms: | SNU-1 |
| Background: | SNU-1 was derived in 1984 by J. Park and associates from a poorly differentiated primary carcinoma of the stomach, taken prior to cytotoxic therapy. |
| Species: | Homo sapiens, human |
| Tissue: | stomach |
| Disease: | gastric carcinoma |
| Gender: | Asian,fmale, 44 years adult |
| Morphology: | epithelial |
| Growth Mode: | suspension, multicell aggregates |
| Doubling Time: | 26 hrs |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 12,13 D13S317: 11,14 D16S539: 9,12 D5S818: 12,13 D7S820: 9,12 THO1: 8,9.3 TPOX: 8,10 vWA: 14 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI1640+10%FBS SNU-1完全培养基，# CBP60501M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Blood Type O; Rh + ,The cells express the surface glycoproteins carcinoembryonic antigen (CEA) and TAG 72. |
| Receptor Expression: | vasoactive intestinal peptide (VIP), expressed |
| Oncogene: | myc +; erb B2 + |
| Tumor Formation: | Yes, reported colony forming efficiency of 1.9% in semisolid medium. Ref |
| Comments: | The cells are L-dopa decarboxylase (DDC) negative. SNU-1 cells were positive for VIP receptors but lacked gastrin receptors. No evidence of amplification or rearrangements was noted in the N-myc, L-myc, myb and EGF receptor genes. The cell line expressed levels of c-myc and c-erb-B-2 RNA that were comparable to other cell lines. There was no expression of the following genes: N-myc, L-myc, c-cis, IGF-2, or gastrin releasing peptide. For more information, please contact Cobioer (4008-750-250). |
