OCI-LY1（人B细胞淋巴瘤）
CBP60557
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| I. General information | |
| Synonyms: | OCI-LY1 |
| Background: | established from the bone marrow of a 44-year-old man with B-cell non-Hodgkin lymphoma (B-NHL; diffuse large cell), stage 4B at relapse in 1983; assigned to GCB-like lymphoma subtype (germinal center B-cell) |
| Species: | human (Homo sapiens) |
| Tissue: | N/A |
| Disease: | B cell lymphoma |
| Gender: | N/A |
| Morphology: | small round to polymorph cells growing singly in suspension; |
| Growth Mode: | N/A |
| Doubling Time: | ca. 50-60 hours |
| DNA Profile: | N/A Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
IMDM+20%FBS OCI-LY1完全培养基，# CBP60557M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Mycoplasma: | negative in microbiological culture, PCR assays |
| Immunology: | CD3 -, CD10 +, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, CD80 +, CD138 -, HLA-DR -, sm/cyIgG -, sm/cyIgM +, sm/cykappa +, sm/cylambda -; image |
| Fingerprint: | fluorescent nonaplex PCR of short tandem repeat markers revealed a unique STR DNA profile |
| Species: | N/A |
| Cytogenetics: | human flat-moded hyperdiploid karyotype with 6% polyploidy; 47(41-48)<2n>XY, +7, der(4)t(4;7)(p14;q22), der(7)t(4;7)(p14;p14)del(7)(q22), der(8)t(8;13)(p13;q13), der(8)t(8;8)(p22;q11), der(10)t(10;14)(p14;q32)t(14;11)(q32;q24), der(11)t(11;14)(q24;q32)t(14;18)(q32;q21), del(13)(q31), t(14;18)(q32;q21), der(18)t(3;18)(q24;q21)t(18;18)(p12;q21); carries t(14;18) rearrangements, some cryptic, effecting juxtaposition of IGH with BCL2; resembles published karyotype |
| Virus | PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/-II -, MLV - |
| Comments: | For more information, please contact Cobioer (4008-750-250). |
