OCI-LY7（人B细胞淋巴瘤）
CBP60559
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| I. General information | |
| Synonyms: | OCI-LY7 |
| Background: | established from the peripheral blood sample of a 48-year-old man with B-cell non-Hodgkin lymphoma (B-NHL, diffuse large B-cell lymphoma, DLBCL, stage 2A, at relapse) in 1984; cells were described in the literature to be EBV-negative, to carry the t(8;14) translocation effecting MYC-IGH and a TP53 point mutation |
| Species: | human (Homo sapiens) |
| Tissue: | N/A |
| Disease: | B cell lymphoma |
| Gender: | N/A |
| Morphology: | round to polymorph cells growing in clusters; |
| Growth Mode: | N/A |
| Doubling Time: | ca. 20-24 hours |
| DNA Profile: | N/A Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
IMDM+20%FBS+0.05 mM 2-mercaptoethanol OCI-LY7完全培养基，# CBP60559M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Mycoplasma: | negative in microbiological culture, PCR assays |
| Immunology: | CD3 -, CD10 +, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, cyCD79a +, CD80 -, CD138 -, HLA-DR +, sm/cyIgG -, sm/cyIgM +, sm/cykappa +, sm/cylambda -; |
| Fingerprint: | fluorescent nonaplex PCR of short tandem repeat markers revealed a unique STR DNA profile |
| Species: | human near-diploid karyotype with 3% polyploidy; 46(42-48)<2n>XY, inv(6)(q12q21), t(8;14)(q24;q32), del(18)(q21.1); carries t(8;14) effecting MYC-IGH rearrangement; matches published karyotype |
| Cytogenetics: | N/A |
| Virus | PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/-II -, MLV - |
| Comments: | For more information, please contact Cobioer (4008-750-250). |
