SK-MEL-1（人皮肤黑色素瘤细胞）
CBP60805
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| I. General information | |
| Synonyms: | SK-MEL-1 |
| Background: | F. Oettgen and associates isolated this line using cells obtained from the thoracic duct of a patient with widespread and rapidly progressing malignant melanoma. |
| Species: | Homo sapiens, human |
| Tissue: | malignant melanoma; skin; derived from metastatic site: lymphatic system |
| Disease: | malignant melanoma |
| Gender: | male, 29 years, Caucasian |
| Morphology: | spherical |
| Growth Mode: | clusters in suspension |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 12,13 D13S317: 11 D16S539: 11,12 D5S818: 12,13 D7S820: 12 THO1: 6 TPOX: 11 vWA: 16,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
MEM + 10% FBS+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) SK-MEL-1完全培养基，# CBP60805M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Antigen expression: Blood Type A; Rh+ |
| Cellular Products: | melanin |
| Tumor Formation: | Yes, in nude mice; forms pigmented malignant melanomas; also forms tumors in the cheek pouch of cortisone treated hamsters |
| Comments: | Electron microscopy revealed pigment granules relating both to synthesis and to phagocytosis. Antibody to this line was detected in 63% of patients with malignant melanoma and in 10% of patients with other diseases. For more information, please contact Cobioer (4008-750-250). |
