U-138MG（人胶质母细胞瘤）
CBP60769
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| I. General information | |
| Synonyms: | U-138MG |
| Background: | This is one of a number of cell lines derived from malignant gliomas (see also ATCC HTB-14 and ATCC HTB-15 ) by J. Ponten and associates from 1966 to 1969. |
| Species: | Homo sapiens, human |
| Tissue: | brain |
| Disease: | glioblastoma; classified as grade IV as of 2007 |
| Gender: | male, 47 years, Caucasian |
| Morphology: | polygonal |
| Growth Mode: | adherent |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 12 D13S317: 9,11 D16S539: 12,13 D5S818: 11 D7S820: 9 THO1: 6 TPOX: 8 vWA: 18 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
MEM + 10%FBS+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) U-138MG完全培养基，# CBP60769M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | Blood Type A; Rh+ |
| Tumor Formation: | No, in immunosuppressed mice Yes, in semisolid medium |
| Comments: | It differs from ATCC HTB-14 in morphology and it has a slower proliferation rate. Mycoplasma contamination was observed and cured by March 1974. NOTE: The two glioblastoma cell lines, U-118 MG (HTB-15) and U-138 MG (HTB-16), reportedly from different individuals have identical VNTR and similar STR patterns. U-118 MG and U-138 MG are very similar cytogenetically and share at least six derivative marker chromosomes. For more information, please contact Cobioer (4008-750-250). |
