BALL-1（人B淋巴细胞急性白血病细胞）
CBP61011
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| I. General information | |
| Synonyms: | BALL-1 |
| Background: | established in 1976 from the peripheral blood of a 75-year-old man with acute lymphoblastic leukemia (ALL) at diagnosis |
| Species: | human (Homo sapiens) |
| Tissue: | N/A |
| Disease: | B cell leukemia |
| Gender: | N/A |
| Morphology: | single round cells growing in suspension; |
| Growth Mode: | N/A |
| Doubling Time: | ca. 48-72 hours |
| DNA Profile: | N/A Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640+10%FBS BALL-1完全培养基，# CBP61011M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Mycoplasma: | negative in PCR assay |
| Immunology: | CD3 -, CD5 +, CD8 -, CD10 -, CD13 -, CD19 +, CD20 +, CD34 -, CD37 +, CD38 +, cyCD79a +, HLA-DR +, sm/cyIgG -, sm/cy IgM +, sm/cykappa -, sm/cylambda +; |
| Fingerprint: | genetic typing showed a short tandem repeat (STR) profile indicated as unique by a search of the international STR database |
| Species: | complex human near-pseudodiploid karyotype; 46(43-47)<2n>XY, der(1)t(1;3)(q32;q25) t(1;6)(p34;p21), der(3)t(1;3)(q32;q25)t(3;15)(p21;q21), der(4)t(4;18)(p11;q21)t(18;1)(q23;q21), der(6)del(6)(q23)t(2;6)(q31;p21), inv(6)(p22q25), t(8;14)(q24;q32)x1-2, del(9)(p22p23)der(9)t(3;9)(q11;p13), t(11;14)(q13;q32), der(11)t(8;11)(q22;q24), del(13)(q13q14), dup(13)(q21q31), der(14)t(14;15)(q32;q21), der(15)t(3;15)(q27;q21), der(15)t(8;15)(q24;q21), der(17)t(8;17)(q24;p11), der(18)qdp(18)(q12q21)t(4;18)(q22;p14), dup(19)(p11p13); sdl with der(14)t(11;14)x2; carries biallelic rearrangements of IGH with CCND1 and MYC, respectively, together with focal amplification of the BCL2/18q21 region which remains unrearranged; resembles published karyotype |
| Cytogenetics: | N/A |
| Virus | PCR: EBV -, HBV -, HCV -, HIV-1 -, HIV-2 -, HTLV-I/-II -, MLV - |
| Comments: | For more information, please contact Cobioer (4008-750-250). |
