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PIK3CA p.Q546R Reference Standard

CBP10325

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索取COA
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产品数据库
Introduction 
Format Genomic DNA
Description PIK3CA Q546R lies within the helical domain of the Pik3ca protein (PMID: 24559118). Q546R has not been biochemically characterized, but is predicted to confer a gain of function to the Pik3ca protein as demonstrated by increased cell survival and transforming ability in cell culture (PMID: 26627007, PMID: 29533785).
   
Technical Data 
DNA Change c.1637A>G
AA Change p.Q546R
Mutation type Substitution - Missense
Zygosity Heterozygous
Allelic Frequency 50.00%
Transcript NM_006218.1
Cosmic ID COSM12459
Chr position(GRCh37) chr3:178936095
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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