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列表

GPCR靶点细胞

Class A（Rhodopsin） Class B1（Secretin） Class C（Glutamate） Orphan and other 7TM Parental Cell

免疫治疗

Fc Effector T Cell Activation Co-Stimulatory Co-Inhibitory Other Immune Checkpoint Combination Cytokine&Growth Factor TAA TLR STING Other

TAA（Mouse Model）

5T4 B7H3 B7H4 BCMA CD123 CD138 CD19 CD20 CD22 CD24 EpCAM CD30 CD33 CD38 CD70 CD73 CD74 CD79 CDHs CEACAMs CLDNs CLEC12A DDR1 DLLs DLK1 EpCAM ERBBs FAP FRα GPC3 GPRC5D GUCY2C IL2R KK-LC-1 LILRBs LRRC15 LY6G6D MET MSLN MUCs Nectin4 OVA PDL1 PSMA PTK7 RORs SLC39A6 SSTR2 TF TFRC TROP2

激酶靶点

AKT AXL BCR-ABL1 BTK BRAF c-Kit CLIP1-LTK CSF1R CSF3R EGFR EML4-ALK ERBB4 ETV6-ARG ETV6-KDR FGFRs FLT3 HER2 JAK2 KRAS MET NTRKs PDGFRA PIMs RET ROS1 Control

示踪细胞

肠肺肝淋巴卵巢脑膀胱皮肤前列腺乳腺舌肾胃血液咽胰腺子宫

耐药细胞

阿霉素多西他赛/紫杉醇氟维司群吉非替尼卡博替尼康士得克卓替尼赛沃替尼顺铂他莫昔芬长春新碱长期雌激素缺乏其他耐药细胞

信号调控

信号调控细胞质粒

其他细胞

BCL2 DMPK Ion Channel Nuclear Receptor SARS COV2 Spike Transporter Other cell models

试剂耗材

荧光素酶检测试剂盒 cAMP 检测试剂盒耗材

激酶靶点

激酶(kinase)是一类非常重要的药物靶点。许多肿瘤的发生是由某些与生长相关的“激酶”发生突变导致异常活化引起的，因而针对这些突变激酶的抑制剂能够有效抑制这些激酶的活性，从而达到抑制癌细胞增长的目的。

Kinase激酶靶点

为了助力小分子药物研发，公海赌赌船官网jc710开发了BA/F3系列的激酶工程细胞株，如EGFR/NTRKs/RET/BCR-ABL1/K RAS/BRAF/MET靶点等，用于评估药物对激酶的靶向抑制作用。

靶点分类

>25 Models

>4 Models

>29 Models

>19 Models

>42 Models

>3 Models

>10 Models

>3 Models

>14 Models

>7 Models

>17 Models

>11 Models

>5 Models

>5 Models

>2 Models

>18 Models

产品列表

靶点	名称	货号
AKT	AKT1 WT/BaF3	CBP73295
AKT	AKT1 E17K/BaF3	CBP73275
AKT	AKT2 E17K/BaF3	CBP73281
AKT	AKT3 E17K/BaF3	CBP73280
AXL	AXL (Gas6 Dependent)/BaF3	CBP73249
AXL	AXL/3T3	CBP73393
AXL	AXL-MBIP/BaF3	CBP73274
BCR-ABL1	BCR-ABL1/BaF3	CBP73001
BCR-ABL1	BCR-ABL1 [T315I]/BaF3	CBP73190
BCR-ABL1	BCR-ABL1[Y253H/T315I]/BaF3	CBP73263
BCR-ABL1	BCR-ABL1 [E255V /T315I ]/BaF3	CBP73277
BCR-ABL1	BCR-ABL1[Q252H /T315I]/BaF3	CBP73278
BCR-ABL1	BCR-ABL1 [Y253H]/BaF3	CBP73287
BCR-ABL1	BCR-ABL1 [E255V]/BaF3	CBP73288
BCR-ABL1	BCR-ABL1 [Q252H]/BaF3	CBP73289
BCR-ABL1	BCR-ABL1 [E459K]/BaF3	CBP73302
BCR-ABL1	BCR-ABL1 [F359V]/BaF3	CBP73303
BCR-ABL1	BCR-ABL1 [P465S]/BaF3	CBP73304
BCR-ABL1	BCR-ABL1 [E355G]/BaF3	CBP73306
BCR-ABL1	BCR-ABL1 [A337V]/BaF3	CBP73307
BCR-ABL1	BCR-ABL1 [V468F]/BaF3	CBP73308
BCR-ABL1	BCR-ABL1 [I502L]/BaF3	CBP73309
BCR-ABL1	BCR-ABL1 [P223S]/BaF3	CBP73310
BCR-ABL1	BCR-ABL1 [K294E]/BaF3	CBP73311
BCR-ABL1	BCR-ABL1 [M244V]/BaF3	CBP73312
BCR-ABL1	BCR-ABL1 [H396P]/BaF3	CBP73317
BCR-ABL1	BCR-ABL1 [E255K]/BaF3	CBP73318
BCR-ABL1	BCR-ABL1 [G250E]/BaF3	CBP73321
BCR-ABL1	BCR-ABL1 [T315M]/BaF3	CBP73322
BCR-ABL1	BCR-ABL1 [M351T]/BaF3	CBP73323
BCR-ABL1	BCR-ABL1 [F317L/T315I]/BaF3	CBP73325
BCR-ABL1	BCR-ABL1[Y253H/E255K]/BaF3	CBP73326
BCR-ABL1	BCR-ABL1 [F359V/T315I]/BaF3	CBP73327
BCR-ABL1	BCR-ABL1[Y253H/F359V]/BaF3	CBP73328
BCR-ABL1	BCR-ABL1 [F317L]/BaF3	CBP73329
BCR-ABL1	BCR-ABL1 [V299L]/BaF3	CBP73330
BRAF	BRAF V600R/BaF3	CBP73385
BRAF	BRAF K601N/BaF3	CBP73386
BRAF	BRAF L597R/BaF3	CBP73387
BRAF	BRAF K601E/BaF3	CBP73388
BRAF	BRAF V600E/BaF3	CBP73389
BRAF	BRAF V600K/BaF3	CBP73390
BRAF	BRAF G469R/BaF3	CBP73396
BRAF	KIAA1549-BRAF/BaF3	CBP73384
c-Kit	c-Kit D816V/BaF3	CBP73206
c-Kit	c-Kit Y823D/BaF3	CBP73208
c-Kit	c-Kit W557_K558del/BaF3	CBP73233
c-Kit	c-Kit V559D/BaF3	CBP73234
c-Kit	c-Kit V560D/BaF3	CBP73235
c-Kit	c-Kit D820Y/BaF3	CBP73236
c-Kit	c-Kit WT (SCF1 Dependent)/BaF3	CBP73269
c-Kit	c-Kit D816Y/BaF3	CBP73276
c-Kit	c-Kit N822K/BaF3	CBP73279
c-Kit	c-Kit D816H/BaF3	CBP73282
c-Kit	c-Kit W557_K558del-V654A/BaF3	CBP73283
c-Kit	c-Kit W557_K558del-T670I/BaF3	CBP73284
c-Kit	c-Kit W557_K558del-D816V/BaF3	CBP73285
c-Kit	c-Kit V559A/BaF3	CBP73286
c-Kit	c-Kit W557G/BaF3	CBP73293
c-Kit	c-Kit K642E-D816A/BaF3	CBP73294
c-Kit	c-Kit A502_Y503dup/BaF3	CBP73296
c-Kit	c-Kit L576P/BaF3	CBP73298
c-Kit	c-Kit V560Del/BaF3	CBP73314
RET	CCDC6-RET WT/BaF3	CBP73214
RET	CCDC6-RET [V804L]/BaF3	CBP73215
RET	CCDC6-RET [V804M]/BaF3	CBP73216
RET	KIF5B(E15)-RET (E12)-long/BaF3	CBP73195
RET	KIF5B(E15)-RET (E12)[V804M]/BaF3	CBP73196
RET	KIF5B(E15)-RET (E12)[V804E]/BaF3	CBP73197
RET	KIF5B(E15)-RET (E12) [V804L]/BaF3	CBP73198
RET	KIF5B(E15)-RET (E12)-short/BaF3	CBP73205
RET	KIF5B(E15)-RET (E12)[G810R]/BaF3	CBP73231
RET	KIF5B(E15)-RET (E12)/3T3	CBP73392
RET	NCOA4-RET/BaF3	CBP73265
ROS1	CD74-ROS1/BaF3	CBP73331
ROS1	EZR-ROS1/BaF3	CBP73324
ROS1	SDC4-ROS1/BaF3	CBP73320
ROS1	SLC34A2-ROS1/BaF3	CBP73191
ROS1	SLC34A2-ROS1 G2032R/BaF3	CBP73192
CSF1R	CSF1R(CSF1 Dependent)/BaF3	CBP73229
CSF3R	CSF3R WT/BaF3	CBP73264
CSF3R	CSF3R Q741*/BaF3	CBP73254
CSF3R	CSF3R S783fs/BaF3	CBP73255
CSF3R	CSF3R T615A/BaF3	CBP73252
CSF3R	CSF3R T618I/BaF3	CBP73253
EGFR	EGFR L858R/BaF3	CBP73040
EGFR	EGFR Del19/BaF3	CBP73045
EGFR	EGFR Del19-T790M/BaF3	CBP73046
EGFR	EGFR L858R-C797S/BaF3	CBP73047
EGFR	EGFR L858R-T790M/BaF3	CBP73048
EGFR	EGFR L861Q/BaF3	CBP73050
EGFR	EGFR G719D/BaF3	CBP73168
EGFR	EGFR G719S/BaF3	CBP73169
EGFR	EGFR G719A/BaF3	CBP73170
EGFR	EGFR S768I/BaF3	CBP73171
EGFR	EGFR Del19-C797S/BaF3	CBP73172
EGFR	EGFR Del19-T790M-C797S/BaF3	CBP73173
EGFR	EGFR D770_N771insSVD/BaF3	CBP73175
EGFR	EGFR V769_D770insASV/BaF3	CBP73176
EGFR	EGFR H773_V774insNPH/BaF3	CBP73177
EGFR	EGFR D770_N771insG/BaF3	CBP73178
EGFR	EGFR P772_H773insDNP/BaF3	CBP73179
EGFR	EGFR D770_N771insNPG/BaF3	CBP73180
EGFR	EGFR S768_V769delinsIL(S768I&V769L)/BaF3	CBP73181
EGFR	EGFR A763_Y764insFQEA/BaF3	CBP73182
EGFR	EGFR D770>GY/BaF3	CBP73183
EGFR	EGFR L858R-T790M-C797S/NCI-H1975	CBP73213
EGFR	EGFR V769_D770insGSV/BaF3	CBP73217
EGFR	EGFR D770_N771insY/BaF3	CBP73218
EGFR	EGFR H773_V774insPH/BaF3	CBP73219
EGFR	EGFR H773_V774insAH/BaF3	CBP73220
EGFR	EGFR V769_D770insSFL/BaF3	CBP73221
EGFR	EGFR V769_D770insGVV/BaF3	CBP73222
EGFR	EGFR H773_V774insPHPH/BaF3	CBP73223
EGFR	EGFR H773_V774insH/BaF3	CBP73224
EGFR	EGFR VIII/BaF3	CBP73226
EGFR	EGFR/MDA-MB-231	CBP73349
EGFR	EGFR L858R-T790M-C797S/BaF3	CBP73382
EGFR	EGFR Del19-T790M-C797S/PC14	CBP73397
EGFR	EGFR WT (EGF Dependent) BaF3	CBP73399
EML4-ALK	EML4-ALK V1/BaF3	CBP73185
EML4-ALK	EML4-ALK V3b/BaF3	CBP73186
EML4-ALK	EML4-ALK V1 [L1196M]/BaF3	CBP73187
EML4-ALK	EML4-ALK V1 [F1174L]/BaF3	CBP73188
EML4-ALK	EML4-ALK V1 [C1156Y]/BaF3	CBP73189
EML4-ALK	EML4-ALK V3a/BaF3	CBP73199
EML4-ALK	EML4-ALK V1 [G1202R]/BaF3	CBP73200
EML4-ALK	EML4-ALK V1 [G1202R/L1196M]/BaF3	CBP73271
EML4-ALK	EML4-ALK V1 [G1202R/L1198F]/BaF3	CBP73272
EML4-ALK	EML4-ALK V1 [G1202R/G1269A]/BaF3	CBP73273
EML4-ALK	EML4-ALK V1 [I1171N]/BaF3	CBP73299
EML4-ALK	EML4-ALK V1 [I1171N/F1174I]/BaF3	CBP73300
EML4-ALK	EML4-ALK V1 [I1171N/L1198H]/BaF3	CBP73301
EML4-ALK	EML4-ALK V1 [G1202R/G1269A/L1204V]/BaF3	CBP73339
EML4-ALK	EML4-ALK V1 [G1202R/G1269A/L1198F]/BaF3	CBP73340
EML4-ALK	EML4-ALK V1 [G1269A]/BaF3	CBP73341
EML4-ALK	EML4-ALK V1 [D1203N]/BaF3	CBP73342
EML4-ALK	EML4-ALK V1 [L1198F]/BaF3	CBP73343
EML4-ALK	EML4-ALK V1 [G1269S]/BaF3	CBP73350
EML4-ALK	EML4-ALK V1 [C1156Y/L1198F]/BaF3	CBP73351
EML4-ALK	EML4-ALK V1 [L1196M/L1198F]/BaF3	CBP73352
EML4-ALK	EML4-ALK V1 [I1171T]/BaF3	CBP73353
EML4-ALK	EML4-ALK V1 [I1171S]/BaF3	CBP73354
EML4-ALK	EML4-ALK V1 [C1156Y/G1202R]/BaF3	CBP73364
EML4-ALK	EML4-ALK V1 [D1203N/I1171N]/BaF3	CBP73270
ERBB4	ERBB4 E452K(NRG1b Dependent)/BaF3	CBP73258
ERBB4	ERBB4 WT(NRG1b Dependent)/BaF3	CBP73257
ETV6-ARG	ETV6(Tel)-ARG/BaF3	CBP73010
ETV6-KDR	TEL-KDR/BaF3	CBP73305
NTRKs	LMNA-NTRK1/BaF3	CBP73202
NTRKs	NACC2-NTRK2/BaF3	CBP73247
NTRKs	ETV6-NTRK3/BaF3	CBP73194
NTRKs	ETV6-NTRK3 [G696A]/BaF3	CBP73209
NTRKs	ETV6-NTRK3 [G623R]/BaF3	CBP73211
NTRKs	QKI-NTRK2/BaF3	CBP73248
NTRKs	QKI-NTRK2[G639R]/BaF3	CBP73261
NTRKs	QKI-NTRK2[G709C]/BaF3	CBP73262
NTRKs	TFG-NTRK1/BaF3	CBP73193
NTRKs	TPM3-NTRK1/BaF3	CBP73203
NTRKs	TPM3-NTRK1 [G667C]/BaF3	CBP73210
NTRKs	TPM3-NTRK1 [G595R]/BaF3	CBP73225
NTRKs	TPM3-NTRK1 [F589L]/BaF3	CBP73259
NTRKs	TPM3-NTRK1 [V573M]/BaF3	CBP73260
FGFRs	FGFR2-AHCYL1/BaF3	CBP73267
FGFRs	FGFR2-BICC1/BaF3	CBP73268
FGFRs	FGFR3-TACC3 [K650N] /BaF3	CBP73377
FLT3	FLT3-ITD/BaF3	CBP73096
FLT3	FLT3-ITD [D835V]/BaF3	CBP73097
FLT3	FLT3-ITD [D835Y]/BaF3	CBP73098
FLT3	FLT3-ITD [F691L]/BaF3	CBP73099
FLT3	FLT3-ITD [Y842C]/BaF3	CBP73100
FLT3	FLT3-ITD [D835H]/BaF3	CBP73239
FLT3	FLT3-ITD [D835E]/BaF3	CBP73240
FLT3	FLT3-ITD [D835del]/BaF3	CBP73241
FLT3	FLT3-ITD [N676K]/BaF3	CBP73242
FLT3	FLT3-ITD [I836del]/BaF3	CBP73243
HER2	HER2 WT/3T3	CBP73394
HER2	Her2 WT/BaF3	CBP73110
HER2	Her2 A775_G776insYVMA/BaF3	CBP73184
HER2	Her2 P780_Y781insGSP/BaF3	CBP73244
HER2	Her2 A775_G776insYVMA/3T3	CBP73256
HER2	Her2 L755S/BaF3	CBP73319
HER2	HER2 P780_Y781insGSP/3T3	CBP73395
JAK2	JAK2 V617F/BaF3	CBP73246
JAK2	TEL(ETV6)-JAK2/BaF3	CBP73117
KRAS	KRAS G12C/BaF3	CBP73227
KRAS	KRAS G12D/BaF3	CBP73228
KRAS	KRAS G12V/BaF3	CBP73230
KRAS	KRAS G12C-Y96C/BaF3	CBP73337
KRAS	KRAS G12C-H95D/BaF3	CBP73338
KRAS	KRAS G12C-R68S/BaF3	CBP73344
KRAS	KRAS G12C-H95Q/BaF3	CBP73345
KRAS	KRAS G12C-Y96D/BaF3	CBP73346
KRAS	KRAS G12C-H95R/BaF3	CBP73347
KRAS	KRAS G12C-R68M/BaF3	CBP73372
KRAS	KRAS G12C-A59S/BaF3	CBP73373
KRAS	KRAS G12C-Q99L/BaF3	CBP73374
KRAS	KRAS G12C-Y96S/BaF3	CBP73376
KRAS	KRAS G12C-A59T/BaF3	CBP73380
KRAS	KRAS[G12D&Y96D] BaF3	CBP73400
KRAS	KRAS[G12D&Y64H] BaF3	CBP73401
PDGFRA	PDGFRA D842V/BaF3	CBP73238
PDGFRA	PDGFRA D842V-V658A/BaF3	CBP73333
PDGFRA	PDGFRA D842V-G680R/BaF3	CBP73334
PDGFRA	PDGFRA D842V-T674I/BaF3	CBP73335
PDGFRA	PDGFRA V658A-R558_I565del/BaF3	CBP73336
PDGFRA	PDGFRA V658A-V561A/BaF3	CBP73378
PDGFRA	PDGFRA V658A/BaF3	CBP73379
PIMs	PIM-1/BaF3	CBP73375
PIMs	PIM-3/BaF3	CBP73292
MET	TFG-MET/BAF3	CBP73391
MET	TPR-MET/BaF3	CBP73365
MET	TPR-MET [D1228N]/BaF3	CBP73366
MET	TPR-MET [F1200l]/BaF3	CBP73367
MET	TPR-MET [L1195F]/BaF3	CBP73368
MET	TPR-MET [Y1230H]/BaF3	CBP73369
MET	TPR-MET [Y1230C]/BaF3	CBP73370
MET	TPR-MET [G1163R]/BaF3	CBP73371
CLIP1-LTK	CLIP1-LTK BaF3	CBP73402