MGMT 甲基化单基因单区段标准品
CBPE0250-0256
询 价
索取COA
产品描述
产品数据库
| Introduction | ||||||
| Description | DNA methylation is an epigenetic modification, a form of chemical modification of DNA, which refers to the carbon 5 of cytosine in the genomic CpG dinucleotide under the action of DNA methyltransferase. covalently bonded to a methyl group. It can change genetic expression without changing the DNA sequence. MGMT, O-6-methylguanine-DNA methyltransferase, is a DNA repair protein that plays a role in removing DNA adducts and regulates cell death. MGMT fusions have been identified in glioma, and MGMT promoter methylation and loss of MGMT expression has been identified in various tumor types, including lymphoma, glioma, colorectal, non-small cell lung, and head and neck carcinoma. |
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| Technical Data | ||||||
| Classification | Cat No. | Name | Unit Size | Methylation level | ||
| Chr10:131265516-131265596(hg19) | ||||||
| 质控品 | 阳性质控品 | CBPE0250 | MGMT Methylation Positive control | 1ug | 98.30% | |
| 阴性质控品 | CBPE0251 | MGMT Methylation Negative control (< Cut off) | 1ug | 0.00% | ||
| 参考品 | 强阳性参考品-1 | CBPE0252 | MGMT Methylation Reference Standard with > 90% | 1ug | 98.30% | |
| 强阳性参考品-2 | CBPE0253 | MGMT Methylation Reference Standard with 10% | 1ug | 10.92% | ||
| 弱阳性参考品 | CBPE0254 | MGMT Methylation Reference Standard with 3% | 1ug | 3.10% | ||
| 检测限参考品 | CBPE0255 | MGMT Methylation Reference Standard with 1% | 1ug | 1.10% | ||
| 阴性参考品 | CBPE0256 | MGMT Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
| 精密度参考品 | CBPE0254 | MGMT Methylation Reference Standard with 3% | 1ug | 3.10% | ||
| CBPE0256 | MGMT Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |||
| 特异性参考品 | 定制化 | |||||
| 备注 | 1. 质控品也叫准确度标准品，用于定性判断； 2. 参考品用于定性和定量的判断，其中强阳、弱阳、检测限、精密度、特异性的判定需要视具体项目而定，本产品的判定仅为内部标准； 3. 质控品用于性能评价，出厂检，试剂盒日常检测判定，参考品用于性能评价，出厂检； 4.上述产品只展示了部分结果，甲基化程度可以定制。 |
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| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 2-8°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
| Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. | |||||
