GITRL/CHO
CBP74094
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| I. Background | |
| GITRL (CD357; AITRL; TNLG2A), a part of the tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18), is mainly expressed on antigen presenting cells. GITRL engages with the GITR receptor as a co-stimulatory signal to promote lymphocyte activation. | |
| II. Description | |
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Recombinant CHO cell constitutively expressing full length human GITRL. Surface expression is confirmed by flow cytometry. |
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| III. Introduction | |
| Host Cell: | CHO |
| Expressed gene: | GITRL |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+400ug/ml hygromycin |
| Storage: | Liquid nitrogen |
| Application(s): | Ligand of GITR&Binding Assay,FACS |
IV. Description of Host Cell Line |
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| Organism: | Hamster |
| Tissue: | Ovary |
| Disease: | Hamster Chinese ovary |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
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Figure 1. Recombinant CHO cell constitutively expressing full length human GITRL. Surface expression is confirmed by flow cytometry. |
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