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CSF3R WT/BaF3

CBP73264

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I. Introduction

Cell Line Name:

CSF3R WT/BaF3

Host Cell:

Ba/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

 
II. Background

CSF3R, colony stimulating factor 3 receptor, encodes a cytokine receptor regulating proliferation and differentiation of myeloid progenitor cells (PMID: 27789332). CSF3R mutations commonly occur in chronic neutrophilic leukemia and acute myeloid leukemia (PMID: 23896413, PMID: 30348809).

 
III. Representative Data

1.WB of  CSF3R WT/BaF3

2. Anti-proliferation assay

Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R WT/BaF3.


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