AXL-MBIP/BaF3
CBP73274
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| I. Introduction | |
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Cell Line Name： |
AXL-MBIP/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II. Background | |
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AXL, AXL receptor tyrosine kinase, is a receptor tyrosine kinase, which promotes growth, migration, and survival of tumor cells through activation of Mapk signaling (PMID: 28072762). Activation and overexpression of AXL has been associated with resistance to chemotherapeutic agents and targeted therapies (PMID: 28251492), in both solid and hematological tumors (PMID: 32148495). |
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| III. Representative Data | |
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1. WB of AXL-MBIP/BaF3
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2. Anti-proliferation assay |
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Figure 2. CTG Proliferation Assay of BaF3 AXL MBIP (C2). |
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