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TP53 p.L194F Reference Standard

CBP10197

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Introduction 
Format Genomic DNA
Description TP53 L194F lies within the DNA binding domain of the Tp53 protein (UniProt.org). L194F results in decreased Tp53 transactivation activity and decreased binding to Bcl2 in cell culture (PMID: 16443602).
   
Technical Data 
DNA Change c.580C>T
AA Change p.L194F
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000269305
Cosmic ID COSM10995
Chr position(GRCh37) chr17:7578269
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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