TP53 p.C135F Reference Standard
CBP10169
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| Introduction | |
| Format | Genomic DNA |
| Description | TP53 C135F lies within the DNA-binding domain of the Tp53 protein (UniProt.org). C135F is predicted to confer a loss of function to the Tp53 protein, as demonstrated by loss of Tp53 transactivation activity in culture (PMID: 16492679). |
| Technical Data | |
| DNA Change | c.404G>T |
| AA Change | p.C135F |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10647 |
| Chr position(GRCh37) | chr17:7578526 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
