4T1（小鼠乳腺癌细胞）
CBP60352
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| I. General information | |
| Synonyms: | 4T1 |
| Background: | 4T1 is a 6-thioguanine resistant cell line selected from the 410.4 tumor without mutagen treatment. |
| Species: | Mouse |
| Tissue: | mammary gland |
| Disease: | This tumor is an animal stage IV human breast cancer. |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Culture Medium: |
RPMI-1640+10%FBS 4T1完全培养基，# CBP60352M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Tumor Formation: | Yes, forms tumors and metastasizes in BALB/c mice |
| Comments: | When injected into BALB/c mice, 4T1 spontaneously produces highly metastatic tumors that can metastasize to the lung, liver, lymph nodes and brain while the primary tumor is growing in situ. The primary tumor does not have to be removed to induce metastatic growth. Because 4T1 is resistant to 6-thioquanine, micro-metastatic cells (as few as 1) can be detected in many distant site organs with better accuracy that most tumor models. There is no need to count nodules or weight target organs. For more information, please contact Cobioer (4008-750-250). |
