T47D（人乳腺癌细胞）
CBP60397
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| I. General information | |
| Synonyms: | T-47D |
| Background: | The T-47 line was isolated by I. Keydar from a pleural effusion obtained from a 54 year old female patient with an infiltrating ductal carcinoma of the breast. |
| Species: | Homo sapiens, human |
| Tissue: | mammary gland; derived from metastatic site: pleural effusion |
| Disease: | ductal carcinoma |
| Gender: | female, 54 years adult |
| Morphology: | epithelial |
| Growth Mode: | adherent |
| Doubling Time: | 32 hrs |
| DNA Profile: | Amelogenin: X CSF1PO: 11,13 D13S317: 12 D16S539: 10 D5S818: 12 D7S820: 11 THO1: 6 TPOX: 11 vWA: 14 Cobioer’s Cell Line Authentication Service |
| Isoenzymes | AK-1, 1 ES-D, 2 G6PD, B GLO-I, 1-2 PGM1, 1 PGM3, 1 |
| Culture Medium: |
RPMI-1640+10%FBS T47D完全培养基，# CBP60397M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | N/A |
| Receptor Expression: | calcitonin, expressed; androgen receptor, expressed; estrogen receptor, expressed; progesterone receptor, expressed; glucocorticoid receptor, positive, expressed; prolactin, expressed; calcitonin; androgen receptor, positive; progesterone receptor, positive; glucocorticoid; prolactin; estrogen receptor, positive |
| Oncogene: | N/A |
| Genes Expressed: | N/A |
| Cellular Products: | N/A |
| Tumor Formation: | Yes, forms colonies in soft agar |
| Comments: | This differentiated epithelial substrain (T-47D) was found to contain cytoplasmic junctions and receptors to 17 beta estradiol, other steroids and calcitonin. The cells express the WNT7B oncogene. Ref For more information, please contact Cobioer (4008-750-250). |
