Mino（人非霍奇金淋巴瘤细胞）
CBP60677
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| I. General information | |
| Synonyms: | Mino |
| Species: | Homo sapiens, human |
| Tissue: | peripheral blood/Mantle cell lymphoma (B cell non-Hodgkin's lymphoma) |
| Disease: | Mantle Cell Lymphoma |
| Gender: | Caucasian, male, 64 years |
| Morphology: | lymphoblast |
| Growth Mode: | suspension |
| Doubling Time: | about 72 hours |
| DNA Profile: | Amelogenin: X,Y CSF1PO: 9,11 D13S317: 12 D16S539: 11,12 D5S818: 11,12 D7S820: 10,11 THO1: 9.3 TPOX: 8,11 vWA: 14,17 Cobioer’s Cell Line Authentication Service |
| Culture Medium: |
RPMI-1640 +15%FBS Mino完全培养基，# CBP60677M |
| Cryopreservation medium: | 90%FBS+10%DMSO |
| Antigen Expression: | CD3-, CD5+, CD10-, CD19+, CD20+, CD23- (verified at ATCC) |
| Oncogene: | p53, p16 (INK4a), and p21(WAF1) |
| Genes Expressed: | cyclin D2 and cyclin D3, p53, p16 (INK4a), and p21(WAF1) |
| Comments: | The cells are large, growing singly and in small clumps in vitro. The immunophenotype by flow cytometry is compatible with MCL. Western blots show expression of cyclin D1 but no detectable cyclin D2 and cyclin D3; the retinoblastoma protein is predominantly phosphorylated. There is expression of tumor suppressor gene products including p53, p16 (INK4a), and p21(WAF1). Ref For more information, please contact Cobioer (4008-750-250). |
