TP53 p.G266E Reference Standard
CBP10174
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| Introduction | |
| Format | Genomic DNA |
| Description | TP53 G266E lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). G266E results in decreased Tp53 transactivation activity (PMID: 20505364), and has been shown to promote cell motility in culture (PMID: 22114072). |
| Technical Data | |
| DNA Change | c.797G>A |
| AA Change | p.G266E |
| Mutation type | Substitution - Nonsense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10867 |
| Chr position(GRCh37) | chr17:7577141 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
