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HIF-Luc/786-o

CBP74213

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I. Background
Hypoxia-inducible factor (HIF) is the major transcriptional regulator mediating the cellular physiological response to reduced levels of oxygen (hypoxia). Upregulated as a consequence, both of intra-tumour hypoxia and through activation of oncogenic pathways, HIF has an important role in the pathogenesis of many cancers.
 
II. Introduction
Host Cell: 786-o
Expressed gene: HIF-Luc
Stability: 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: RPMI-1640+10%FBS+150ug/ml hygromycin
Storage: Liquid nitrogen
 
III. Description of Host Cell Line
Organism: Homo sapiens, human
Tissue: kidney
Disease: carcinoma
Morphology: epithelial
Growth Properties: adherent
 
IV. Representative Data
 

 

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